Florida has a ton of great places to stay, and renting a house or a condo would be a great idea with a group of that size.Rather than give you a specific property name and location, I would suggest that you do some research on the available houses/condos, the prices and the locations within Destin. I have used justvr.com in the past and it was quite helpful for narrowing down my choices and booking a few nights stay.
Try HomeAway.com for condos/apartments. TripAdvisor.com has destination guides and lists of hotels/resorts, along with comments on them by past guests.