It constantly amazes me how many Answers out hear do not read questions closely and therefore give screw-up answers, as did the 2 Answerers before me here.OK, to beat the (presumably weekday rush hour) traffic from Boston to Maine (and not vice-versa, as the previous Answerers responded to) you should leave Boston by 4pm, maybe even 3:45, or after 6:30 pm.
i left boston l one summer night at 10pm...i had the whole highway to myselfabout 90% of the time......buy cupS of coffee before you leave, everything seems closed
The earlier the better, I would leave at about 400 am
honestly prob 4-5am u will be good trust me