I ve recently seen Mystere @ Treasure Island and had a blast. During the show the closest rows to the stage get to be a part of the show and some of the stage actors randomly pick audience members to be a part of the show. No your necks won t be strained from watching you ll have the best view! =)Have Fun!!
You want the bottom section by the stage, center area if possible. Because there is a pre-game entertainment make sure you have a box of popcorn. And no you do not want right at the stage, more like 8 rows back. BTW all seats are good