The train will take 14 hours. It is called the Coast Starlight (Amtrak) and it goes once a day. Another option is to take the train to Los Angeles (this train, the Pacific Surfliner, goes every hour) and then a shuttle (cashuttlebus.com) to SF.
hey buddy! yes its possible to use a train, it will probably take about 4-5 hrs by train, unless it stops to pick up other passengers on the way. I actually drove from san diego to san francisco once, it took almost 9 hrs, I stopped a few times to eat, it as actually quite lovely by the way. San fran is beautiful, its so different, however there are alot of cloudy days but its still a beautiful city, the atmosphere is amazing, hope this helps!
Actually the train takes about 14 hours and it goes to Oakland. Then they bus you into San Francisco.Go to amtrak.com for more information.This is a very secnic way. But if you want fast, you go Southwest Airlines.
If you book 14 days in advance, you can get great rates from http://wwwsouthwest.com. It s faster and cheaper to fly than to take the train.