Better yet avoid the four major metros. You go through Charlotte, but avoid Washington, Baltimore, Philly, and New York.In South Carolina, take I-26 up to Columbia. There you get on I-77 and take that north into Virginia. Take I-81 north up to Scranton, PA. There you ll take I-84 East to Connecticut. Take I-91 North to Vermont, get off at Exit 3 and follow the signs the last 15 miles over the river to Keene.If you just want to miss New York, get off the NJ Turnpike at Exit 11, take the Garden State Parkway north into New York. Take the NY Thruway south over the Tappan Zee Bridge. Take 287 east back to 95.
When you get into new jersey, get off the turnpike at exit 11, then get right on the garden state parkway. Take that straight up into new york. When you cross the state line, go a short distance to the Tappen Zee Bridge. You can cross the Hudson River there. Just go straight to Rt 95 in Conn., and you will be back on your way.