Trains I can cover. Pittsburgh to Philadelphia on the Amtrak Pennsylvanian. http://www.amtrak.com/servlet/ContentSer�� You get the Horseshoe Curve outside Altoona, the fabulous stone bridge crossing the Susquehanna River at Harrisburg, The Big Valley outside Lancaster with Amish Farms, Philadelphia Art Museum up on the hill. Beautiful trip, all in daylight. Bus -- not so much. It s the PA Turnpike all the way. And it s a BUS. The other option is the Capitol Limited, Pittsburgh to Washington, DC. http://www.amtrak.com/servlet/ContentSer�� (Click on the Route Guide) From Philadelphia, you can get a bus up to the Poconos, or to the Jersey Coast. Whatever you do, reserve ASAP. You have picked the busiest season.
Those are peak travel days, and you will pay a lot extra even if you re able to get reservations. They are probably booked up solid by now.