If you re into crowded, touristy areas, start with Times Square and branch out from there. It s hard to go wrong in Manhattan, and the outer boroughs have lots to offer. I don t see how you re going to get a good answer on here unless you try to be more specific, though. I would advise you to google nyc go , which is the tourism promotion program for the city online. Native New Yorker - Nightlife is not a landmark.
May I recommend the following.Landmarks-Empire State Building-Statue of Liberty/Ellis Island-Rockefeller Center and the Top of the Rock Observation Deck-Times Square-Lower Manhattan/Wall Street Area-United Nations-Central Park-Brooklyn Bridge (you can walk across it too)-Grand Central Terminal (largest railroad terminal in the world)-A Ride on the Staten Island Ferry (its free and you can see the Statue of Liberty as the ferry crosses the harbor)-Sightseeing tour on a Double Decker Bus-The Museums-Broadway Show-Shopping.Good luckNative New Yorker
The link below can help u. Good luck!